What is neuropathic pain?

Classification: central peripheral


How do you explain concept of neuropathic pain to patients (sparking wire?)

What pathophysiology is involved (neuroma, sodium channels, ectopy, DRG, central sensitization)?

Adrenergic nervous system and neuropathic pain

Dieback theory of nerve degeneration

Sunderland’s classification nerve damage

Inherited forms of neuropathic pain (Fabry’s, congenital insensitivity to pain, erythromelagia, paroxysmal pain syndrome)

Role of POST and QST

Discuss positive and negative examination features

Screening tools: DNQ LASS, PainDETECT

Screening blood tests for peripheral neuropathy

Basic nerve conduction tests & EMG, sural nerve biopsy


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